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Caution! Eye damage from isopropyl!

Posted on Poppers Guide's Forum

Topic created by achimo
on Thu, 13 Jun 2013 at 18:27

achimo said on Thu, 13 Jun 2013 at 18:27...

I used poppers for many years. But now I have a visual impairment by isopropyl evidence. This found an eye clinic in Berlin. Stop the permanent use! Do not play with your health. You will regret it. It is hard for me to quit, but now I have no choice!

Ronald McReagan said on Wed, 4 Sep 2013 at 07:52...


How often, how much was too much? Did you overdose?

Punkah Wallah said on Sat, 7 Sep 2013 at 16:06...

There is some dude elsewhere saying that doing a "lot of Rush" made him wheezy. Another wanting to take it on an aircraft! Looks like there are some serious pinheads out there. Poppers were never meant to be a lifestyle.

Kojo said on Tue, 10 Sep 2013 at 16:35...

You will be surprised about that. There are people who keep many bottles in a fridge and never leave the house without some....going cruising or whatever.

Popgoes said on Mon, 30 Sep 2013 at 08:53...

Here's an article about rare visual side effectshttp://www.nejm.org/doi/full/10.1056/NEJMc1005118

I've also read it's especially risky if you have a predisposition for macular degeneration.

achimo said on Sun, 3 Nov 2013 at 20:37...

Hello again,
i used Poppers mostly via Gasmask. And this 2-4 times a´ week.
Now i know, that Isopropyl make my Macular-Degeneration calls
We all know, that we get blue nails and mucosa after consum Isopropylnitrit. And this I think is an reaction of nitric oxide and to less oxygen in our blood, that is why we will be blue !!!
And this lack of oxygen and nitric oxide destroyed our retina.

So, i stoped inhalation from Isopropyl immediately. But masturbating without is very very unamusing.
2 Weeks ago i buy the old Isobutylalkohol, Sodium-Nitrite and Battery-Acid and mix my new (old) Poppers self.
That is Okay and i get no blue nails and mucosa. I have with this more than 10 years no problems.
In November i have the next date at my doctor. Than i get my first
eyeglasses. The Pills from the Doctor in Berlin for boosting the macula i take every day. I hope it will be better.

Guys, be carefull. Used Isopropyl when it´s possible not more. And when, not over the Gasmask and not so offten !!!

Sorry for my bad english :-)


WEASEL 1 said on Sat, 17 May 2014 at 21:22...

Poppers with Isopropy inside does effect the retina causing the eye to not be able to focus on fine detail...i think it damages the light receptors in the retina.Once you stop using them it takes a lot of months for the retina to recover .French doctors seem to think it is reversible if you stop poppers.

Motorhead said on Tue, 22 Jul 2014 at 13:51...

achimo: how are things now?
I too am suffering from side effects for some weeks now...

Edulus said on Sat, 26 Jul 2014 at 19:56...

Hallo Achim!

I also have the problem after using poppers. :-(

What kind of Pills did you get from your doctor? Do you know the name?



Andy UK said on Tue, 19 May 2015 at 01:26...



Poppers linked to permanent and serious vision loss

31 October 2014. Related: News.
This is a pre-press article for the November/December edition of HTB.

Simon Collins, HIV i-Base

Serious vision loss linked to recreational use of poppers has been reported as a case study in this weeks issue of the Lancet. The vision changes have not resolved after six months.

Anna M Gruener and colleagues from Guy’s and St Thomas’ NHS Foundation Trust and Queen Mary’s Hospital, Sidcup published a case of maculopathy associated with use of poppers in the 1st November 2014 edition of the Lancet.

This case involved a 30 year old man with no ocular history who presented with bilateral central vision loss following inhalation of poppers. Visual acuity was 6/12 in the right eye and 6/18 in the left eye.

Further examinations showed subtle macular changes in the form of yellow foveal spots by slit lamp biomicroscopy and clear disruption of the foveal cone inner segment—outer segment layer by spectral domain optical coherence tomography.

Neither visual acuity nor examination findings have resolved despite no further use of poppers for six months.

The report notes that other cases of poppers maculopathy have been reported since legislation in 2006 led to isopropyl nitrite being changed to isobutyl nitrite. The report notes that the mechanism for poppers to damage central photoreceptors is unknown, but that there is a clear cause-effect relationship, and that reports are increasing.

The authors note that the risk of damage is potentially serious and irreversible.

Poppers is the common name for a stimulant commonly branded as a room odouriser but which is inhaled as a recreational drug to enhance dancing or sex, or both.


Details on the estimated exposure to poppers that prompted these symptoms or previous history of use are not included.

One of the purposes of a case study is to highlight previous unknown or underestimated serious events. This should prompt further research that might be able to evaluated how common this might be.

People using poppers, even with no previous history of eye problems should be aware that this is a potential risk. I also raise concerns for sub-clinical damage that may not be reported but might have longer term consequences.

Further details may be available for the print edition of this report.


Gruener AM et al. Poppers maculopathy. The Lancet, Volume 384, Issue 9954, Page 1606, 1 November 2014. doi:10.1016/S0140-6736(14)60887-4.

Ralf said on Thu, 14 Apr 2016 at 18:16...

I have been a user of poppers bought locally since around 1996. Never a heavy user but regular ( a few times a year) Never had a problem until around 2008 when i noticed vey little effect and they smelled different. I now know this was around the time they switched to using a different chemical. Because less effect you tend ti inhale more deeply. Next day driving to work and using computer monitor i noticed my central vision was just not there and everything looked bright and fuzzy. Because of goverment interference we seem to have moved from a relativly safe product to something that can cause you to go almost blind with repeated use!

Harry said on Fri, 15 Jul 2016 at 22:26...

I have permanent serious neurotoxic and ototoxic symptoms from poppers. My life has become a living hell after a one night binge on poppers. Warning to everybody out there...you could be next ...never thought it would happen to me.

Thomas said on Thu, 24 Nov 2016 at 17:20...

I am 50 now and only started using Poppers about 3 years ago. I have used up about 2 small bottles ("jt" or "ji" brand) since. About a year ago I noticed having trouble reading books, as there was a slight distortion near the central focus area. Over the months, it got much worse. Eventually I went to a doctor and had to pay 80€ to get an eye exam with a high-end machine for taking a retinal depth scan (OCT). The diagnose was macular degeneration, indeed - which is not uncommon, but rare at my age. So I kept wondering what's causing this, eventually googling for a connection between poppers and this eye problem - and that's when I found this and many other warnings. Had I only known! Now I my left eye is pretty useless for reading (it's quite blurry), thanks to no one knowing of this risk, apparently. Even the three eye doctors I talked to did not think of even asking whether I was using Poppers. There's one little note about this at least on the German WP page. That's a start.

Phillp a said on Wed, 15 Feb 2017 at 04:46...

Hey everybody. So I used poppers Thursday Friday and Saturday night. The brand was rush. I've used them before but they were always somebody elses. I got my own and decided to kind of indulge. Definitly was doing more than I should have every session. Now it's Tuesday and I havnt done them since but I've had a headache that keeps coming and going as well as some pain behind my eyes but no noticeable vision loss or blurryness. Head seems to hurt mostly at the top or in the bqck if that means anything. I never get headaches and am usually a health nut otherwise. Any advice would be appreciated. Don't think I'll be doing these at all anymore.

Motorhead Sherwood said on Mon, 6 Mar 2017 at 09:04...

For more information on poppers and eye damage go to http://poppersguide.com/forum/10213

victoria said on Thu, 7 Sep 2017 at 05:42...

Hi i have read all the post here and i know what you are going through,i have been a tranny since i was 16 and now im 66 i have used poppers nearly all my life the earlier ones the best high ever,i have problems with my eyes now using all this shit they have produced,there is no cure for me,but please stop using this crap from the sex shops now,all you are doing is your eyesight not getting high like we all do,wanking without poppers is no good ,i have been fucked with poppers and enjoyed every minute,i feel like taking this goverment to court over changing the contents of poppers.
Let me know if you can get hold of the original poppers i will be there have a big cumming out party

Love to All


Motorhead Sherwood said on Thu, 28 Sep 2017 at 08:39...

http://poppersguide.com/forum/10213 is closed

i hope posters will find this thread
(so http://poppersguide.com/forum/10054)

Stay away from IPN

D Andrews (The end) said on Mon, 2 Oct 2017 at 10:16...

So, here it goes

following on from posts @ http://poppersguide.com/forum/10213

I was ridiculously stupid, gave in and bought some "expensive poppers" from Australia to see if I could have a sniff here & there without wounding my health.

I got everything ready like I used to... awesome porn, lube and poppers (you know the drill) and you know what... I took 4 sniffs & HATED it. The worry of damaging my eyes, the "being careful" not to over do it, racing heart feeling etc clouded over the whole enjoyment so I instantly stopped and got rid.

I have spent the past 9 months abstaining from poppers, masturbating/fucking enjoying the natural feeling, but missing poppers a little and I have actually come to realize I can have just as good time without it. I enjoyed it while it lasted except the health concerns.

I probably wont post again as I am relatively happy with my health, eyes are slowly improving etc so I wish you guys all the best in the future.

M.Sherwood, hope you are well and abstaining since the last relapse.

All the best,


Bert said on Sun, 15 Oct 2017 at 23:47...

I have a follow up appointment with the ophthalmologist next week, hoping they confirm all is well

Motorhead Sherwood said on Mon, 23 Oct 2017 at 07:29...

Bert, how did your appointment go?

(any one know about an alternative thread that continues 10213?)

Bert said on Thu, 26 Oct 2017 at 15:40...

As I expected, all heading in the right direction. Ophthalmologist agreed taking Lutein supplements is helpful. The damage is vastly improved and the scans of the back of my eyes agree. A small amount of damage remains, more so in one eye, so I’ll have another follow up in three months.

Motorhead Sherwood said on Fri, 27 Oct 2017 at 08:00...

Bert: great to hear!

AnotherVictim said on Tue, 19 Dec 2017 at 22:28...

Tried Isopropyl once, a month ago. Same problems

Motorhead Sherwood said on Thu, 21 Dec 2017 at 10:10...

I have received information that Prednisilone may help with the floaters some people have mentioned in the old thread.

AnotherVictim said on Sat, 23 Dec 2017 at 06:11...

Hi everyone and Hi Motorhead! Yes thanks to all for the invaluable information on here. I sniffed a small amount of isopropyl about 5 weeks ago and had the blind spots which are still with me but gradually going. I wanted to post here because 2 posters, D.Andrews and Sissy mentioned things which sounded slightly different, namely floaters. I'd never touched isopropyl until 18th Nov 2017. Going back to 2007 therefore nothing to do with poppers, I found myself with hundreds if not thousands of floaters in my vision. This was not just a few...it looked as if someone had splattered black ink across whatever I was looking at. One day I was in a bright sunlit room with white walls when I realised that something was wrong so I immediately went to Boots opposite and booked an eye test......(continued)

AnotherVictim said on Sat, 23 Dec 2017 at 06:31...

.....the optician was great! He said that there seemed to be something strange in my eyes that he couldn't explain and immediately booked me up for an appointment at my local eye hospital. They did a thorough examination and found that I had a macular pucker aka epiretinal membrane and I was introduced to a remarkable young man who asked me a few questions eg had I had any Deep Vein Thrombosis? Yes I had. Was I feeling tired? Yes I was. Did I have aching limbs? Yes I did. Any mouth ulcers? Mouth ulcers? I asked. What's that got to do with my eyesight? Well you're ticking all the right boxes for a disease called Behcet's Disease but it's very rare and if you haven't had any mouth ulcers which are a symptom of Behcet's then I can't diagnose you with that....(continued)

AnotherVictim said on Sat, 23 Dec 2017 at 06:50...

...what I can do is prescribe you some eye drops, he said. They're called Pred Forte and they are a cortico steroid. OK thanks I said. After a few days with the prednisilone eye drops, the floaters were gone. I went back for another checkup fully expecting to have to have an eye op to drain my eyes and have them refilled with an artificial gel but I didn't need it. Still at the back of my mind I was convinced that I had Behcet's Disease.

And a year or so later, I was covered in blisters from head to toe and spent a few days in bed before I went to see my GP who called for a second opinion who said I had chicken pox!! Bollocks I thought! That evening I was in agony and called another GP and I told him: "It's Behcet's Disease". He did nothing. The next day I drove myself to A&E

AnotherVictim said on Sat, 23 Dec 2017 at 07:09...

At my local hospital I booked myself in with Behcet's Disease. Gosh that's rare said the lady who booked me in, I've been here 15 years and we've only ever had 2 cases!

I was right. It was Behcet's Disease. I was in hospital for 3 days.

So what's this got to do with Isopropyl Nitrite? Well only that I've had regular eye check ups for the last decade and I know that IPN has given me a new problem. To be honest, I just couldn't bring myself to go to my specialist and admit that I'd done something so daft. I've not been due for a checkup since I did it but to D.Andrews and Sissy I say this:

Insist that you are given predniscilone eye drops because, like me you may have another issue that isn't due to IPN. Remember that I had to go above 3 GPs in one day before I went to A & E. I have little faith in GPs but I have every faith in specialists. And JuniorEyeDoctor on here too!

Anonymous said on Sat, 23 Dec 2017 at 07:33...

One of you said that these floaters looked like cells under a microscope. Well that's exactly what they are. Floaters are dead cells floating around the eye. In my case caused by inflammation of the blood vessels. The blood vessels get inflamed and are unable to supply enough oxygen to the eye, so cells die and become floaters. Steroids restore the oxygen to the eye cells.

D Andrews said on Mon, 1 Jan 2018 at 20:21...


Figured it’s may be beneficial for others if I post this.
I remember it was frustrating that not many users reported back in the later stages of using poppers.

Basically, i am still left with sensitive eyes.

1. Enlarged natural scotoma (blind spot)

2. Bright lights / daylight highlight my floaters (many of them)

3. Under florescent lighting I have many hazy/blurry particales that move with my eyes so they must be floaters too.

4. eyes are both constantly bloodshot (been this way since I stopped (January 2017) I have tried soothing eye drops / gels - nothing helps.

5. I feel my brain isn’t as “switched on” as it used to be, I have read inhalants have damaging effect on the brain like brain shirkage, neurotransmitter blockages, serotonin surpressing, lowering IQ etc... I hope it could be me just looking into things to much but I feel low about it.

I have been clean a year now, I have a follow up eye appointment with the eye specialist in a month and will enquiry about Predniscilone you mention ‘Another Victim’ - problem is they see no problem with my eyes, I have 20/20 apparently and my field view test came back “normal”. They think I am being hypersensitive.

Any tips you lot have in regards to reversing effects of poppers would be appreciated.

I wished for more progress to be honest.

All the best for the new year.

AnotherVictim said on Thu, 4 Jan 2018 at 02:11...

Thanks, D.Andrews and I hope Sissy sees this too. My apologies for forgetting to fill in my username on my last post which came out as "anonymous" but that is me. To everyone else and particularly "Motorhead", it's been a huge help and I just wish I'd seen these posts before I had sniffed that stuff Isopropyl Nitrite.

It has been 6 weeks since I did it and I still have the problem of people's faces in bright light from a distance and I'm taking the Lutein/ Xeazanthin supplements. I think it's slowly improving and at least I don't concentrate on it too much. I think I sniffed about half a teaspoon of the stuff.

Anyway.... (continued)

AnotherVictim said on Thu, 4 Jan 2018 at 07:01...

...I was listening to Radio 5 live yesterday and they were talking about Crohn's Disease which is similar in many ways to Behcet's Disease and one woman phoned in and said that she'd had uveitus with Crohn's Disease. That's what I had. Uveitus. Both Behcet's and Crohn's are problems with the immune system. When I was in hospital in 2010 they tested me for HIV (another autoimmune disease). I could pretty much categoretically state to them that I was not HIV positive! Because I knew I wasn't. But I thought I'd better let them test me for HIV just to satisfy them!

But HIV, Crohn's and Behcet's are ALL immune problems. When I was diagnosed with Behcet's they took me off Pred Forte eye drops and put me on Prednisilone pills for a few months with alendronic acid to stop the steroids from giving me osteoporosis. Then they prescribed Imuran (an immuno-suppressant) in place of the steroids.

This isopropyl nitrite is REALLY NASTY stuff. I see that people have mentioned that it buggers up the immune system and I think they're right. I'm also asthmatic and that isopropyl has had me reaching for the salbutamol (Ventolin) many, many times a day! Isopropyl Nitrite is really evil stuff!

AnotherVictim said on Thu, 4 Jan 2018 at 07:25...

I'm a 48 year old heterosexual male from Brighton. My ex-girlfriends (or girl-fiends) as I like to call them are the scum of the earth. Nasty little cunts! I wish I were gay!

Motorhead Sherwood said on Wed, 31 Jan 2018 at 08:38...

this survey is from the old thread:

The purpose of this survey is to collate the results of those who have (and have not) recovered, to help determine the factors that influence recovery.

If you have had any significant changes since your last entry, feel free to make a new entry.

Make a survey entry here: https://1drv.ms/xs/s!ArRxGrQKKJUNgZgeptlAO19OpZQz8Q

You can see the results of the survey here: https://1drv.ms/x/s!ArRxGrQKKJUNgZgehP6t4uQJXVi0pA

Bert said on Fri, 23 Feb 2018 at 15:44...

Been given the all clear by the hospital, fully reversed damage done by popper use

Motorhead Sherwood said on Mon, 26 Feb 2018 at 11:52...

Bert, great to hear!!

How long did it take to recover completely?

Motorhead Sherwood said on Tue, 27 Feb 2018 at 11:52...

i checked the old posts of Bert (http://poppersguide.com/forum/10213). he noticed the symptoms around may/june 2017.

very encouraging news (and thanks for the feedback)

Ryan said on Wed, 28 Feb 2018 at 12:43...

Not used poppers since July 2017.Eyes are getting better but very very slowly.Probably need another six months.Noticed original damage to eyes when i looked at computer and couldnt see the writing properly..also phone writing same.Also car number plates difficult to see...Now can see number plates further distance away and can read slightly better ...sight not how it was yet though but improving very slowly.Key is not using poppers..isopropyl ..or recovery may be back to beginning.

Bert said on Wed, 14 Mar 2018 at 11:23...

Thanks for checking back Motörhead, complete abstinence was the key. The consultant was somewhat sceptical about the use of lutein based products to aid in recovery as these products are designed for age related maculopathy - any evidence that it could help is anecdotal.

Good luck all.

D Andrews said on Mon, 19 Mar 2018 at 09:30...

I have also got the all clear.

I was told by the ophthalmologist that I had no signs of damage from poppers at all (poppers maculopathy)... She thought it was just age related (I am below the age of 30 so find this hard to believe)

I had my eyes checked in numerous ways along with a brain MRI and ears tested. No problems found in any test. I still have floaters in my eyes and feel damage is done but trying to carry on and hope I recover enough to forger this horrible ordeal.

All the best

Motorhead Sherwood said on Mon, 26 Mar 2018 at 07:57...

Good to hear, D Andrews!

Strange they couldn't find anything wrong with you...

Motorhead Sherwood said on Wed, 27 Jun 2018 at 07:19...

I started using again and I have the impression that the formula has changed again: the blueness is still there but the eye problems are much less. Anyone?

Justin said on Sat, 7 Jul 2018 at 15:32...

I have pretty much lost vision in my right eye from the new version of poppers since around January 2017. Has anybody heard wether a class action case has been pursued for this?

D Andrews said on Mon, 3 Sep 2018 at 13:12...

Update: 95% back to my former self. My eyes continue to have floaters and the blind spot is still noticeable to a less degree. I have not touched poppers for a long time and do miss them.

Motorhead - Do you think the new formulas are better in regards to eyes? Hope you are well.

I have heard good things about Poppers-aromas.eu but scared to get back into poppers from the last experience.

D Andrews said on Thu, 13 Sep 2018 at 12:19...

I fucked up. Bought some from Poppers-aromas.eu which to be fair seemed ok as many have suggested, did not make me turn blue etc

On the other hand I only had 3-4 hits (not hard ones) and must admit I was too worried to enjoy the feeling, constantly checking my eyes in the mirror to see if they were bloodshot, just ruined the experience.

Lesson learnt, I relapsed and need to stay away. I feel ashamed of myself but maybe I am being too harsh, I have stayed away for 13 months so whats one little fuck up right ?

I love masturbation, but its time I found a new hobby.

AnotherVictim said on Sat, 22 Sep 2018 at 03:22...

Thought I'd return for an update and to thank everyone on here again for invaluable advice and experience. Just to recap, I only tried isopropyl nitrite once back in November last year and immediately had the blind spot. I have annual eye checkups at the local eye hospital (where they are rigorous) for a pre-existing medical condition and they said everything was fine when I went on Monday. I'd not mentioned anything about poppers.

It's taken 10 months and my sight is now back to normal after never touching the stuff again. It's a shame, because I thought I'd found a safe high but my eyesight is more important.

It has been a long, slow and gradual process and I believe total abstinence from Isopropyl is the only answer, though I realise that can be difficult.

My best wishes for recovery to all and I'll come back on here to hear how everyone's progressing.

Many thanks.


Recent tries. said on Sat, 13 Oct 2018 at 10:24...


A month back i bought some Isopropyl poppers in the UK, Which i think they are stronger than any Amyl or Pentyl that i got from france afterwards.

The thing is that i started with Propyl without knowing the problems related to eye damage. So, after using them for 3-4 days once a day for no more than 15 to 40 minutes tops anything from 10 to 18 niffs. "I don't recall ever reaching 20". I noticed some floaters in my eye sight which led me to look for the reasons on why was this happening. So after 2 weeks i got some Gate brand "Amyl" and lockerroom Jungle Juice black "Pentyl" accordingly one was manufactured in France the other one in Canada, i tried them both in different days only for 2 days, and both of them gave me the same effect on my eye sight this time probably worst. Just to be clear, i'm a healthy 30yrs old, No illness what so ever and had an almost perfect sight "if not perfect" I probably do one joint of weed once a week but that's it.

In conclusion i stopped for good and started taking some MSM and Anti-oxidants to help recovering my sight hopefully it gets better with time. But this damn floaters are fucking up my life that without saying that my eye gets very sensitive to bright light, you name it... (PC monitor, TV, Smartphone screen, Blue sky, etc.)

Just doesn't worth it.

And another victim said on Sun, 22 Nov 2020 at 23:53...

I've followed this thread for a while. I'm a late 50's, straight male and started using poppers once or twice a week about 20 years ago. Also detected the recipe change and a reduction of effect. I too also noticed eye issues but did not link them to popper use, but then I did so stopped using. My symptoms were light sensitivity, constantly seeing stars and the appearance of numerous eye floaters. Then I relented and bought another bottle and immediately regretted it. Almost overnight more floaters appeared and that could not have been coincidental.

I'd be interested to hear if anyone has had the issue with poppers other than Isobutyl / propyl, I am lead to understand that Amyl Nitrate is ok but too cautious to try.

JoshVR said on Wed, 17 Feb 2021 at 09:01...

Check out thetruthaboutpoppers.com

They warn you they aren't for human consumption. If you choose to inhale the fumes that are strong enough to melt plastic, be strong enough to take ownership of the damage that you have done and the risk you took in order to achieve that brief 20 second high

Popper eard said on Thu, 4 Nov 2021 at 19:33...

Has anyone fully recovered eyesight

Jimbo said on Mon, 7 Mar 2022 at 17:05...

I got some imports with a mask and it burned my throat. That caused bronchitis which let to pneumonia. That was hell. I collapsed with a High fever and needed emergency help.

Michael said on Mon, 7 Mar 2022 at 17:07...

I have friends who work in adult book stores with video booths. They frequently have people pass out and have life threatening heart problems from poppers.

Michael said on Mon, 7 Mar 2022 at 17:21...

I fell over and broke my hip because it's very easy to. pass out. I still desire poppers tho, when watching porn. I huff poppers in plastic bags to blow my mind.. After I broke my hip the surgeon suspected I passed out from using drugs but I denied it. An MRI shows brain shrinkage. Boys let's admit it, the poppers high is addictive. I do it less now but I still want it badly with porn. Why can't I quit?

Jimbo said on Mon, 7 Mar 2022 at 17:29...

I can't quit either. I love porn with a blow job and poppers.
I get carried away and usually spill it so I get two bottles and then I need more and more.
I try to find the strongest poppers and I find ways to huff with pot. I like blowing my mind.
I know it's harmful. Seriously, it is harmful even just once but most of us do it for hours at a time, wanting to cum over and over until we throw it out or pour it out, the only way to stop until the next time.

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